Fig. 2
From: Doxorubicin inhibits osteosarcoma progression by regulating circ_0000006/miR-646/ BDNF axis
DOX exposure inhibited cell proliferation, migration and invasion, and circ_0000006 knockdown contributed to these effects in OS cells. A Circ_0000006 expression was determined after circ_0000006 knockdown by qRT-PCR in U2OS and SJSA1 cells. B, E Cell viability and cell colony formation assays were performed to reveal the effects between DOX treatment and circ_0000006 depletion on cell proliferation in U2OS and SJSA1 cells. C, D Transwell migration and invasion assays were performed to testify the impacts between DOX exposure and circ_0000006 depletion on the migration and invasion of U2OS and SJSA1 cells. *P < 0.05