Fig. 1
From: Doxorubicin inhibits osteosarcoma progression by regulating circ_0000006/miR-646/ BDNF axis
Circ_0000006 was lowly expressed after DOX treatment in OS cells. A, B QRT-PCR was performed to detect circ_0000006 expression in 20 pairs of OS and normal bone tissues and hFOB 1.19, U2OS and SJSA1 cells. C RNase R treatment assay was employed to illustrate that circ_0000006 was a circular RNA. D, E Cell viability assay was used to determine the optimum concentration of DOX in U2OS and SJSA1 cells. F The effect of DOX exposure on circ_0000006 expression was revealed by qRT-PCR in U2OS and SJSA1 cells. *P < 0.05 and **P < 0.01