Fig. 7

There was an interaction between circ_0045714 and PIK3R3 via miR-331-3p. A The correlation coefficient (r) between circ_0045714 and PIK3R3 mRNA in OA cartilages (n = 20) was determined by Pearson correlation test. B, C Western blotting detected relative PIK3R3 protein expression in HAC cells transfected with si-NC, si-circ_0045714, or si-circ_0045714 coupled with anti-miR-NC or anti-miR-331-3p, empty vector, oe-circ_0045714 vector, or oe-circ_0045714 vector coupled with miR-NC or miR-331-3p mimic. *P < 0.05