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Fig. 6 | Journal of Orthopaedic Surgery and Research

Fig. 6

From: FGD5-AS1 facilitates the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells via targeting the miR-506-3p/BMP7 axis

Fig. 6

Silence of BMP7 abrogates the promotion effect of the miR-506-3p inhibitor on osteogenesis of hBMSCs. A RT-qPCR analysis showed the BMP7 expression in hBMSCs transfected with shNC or shBMP7. B RT-qPCR analysis showed the OCN, OPN, and RUNX2 levels in hBMSCs transfected with NC inhibitor, miR-506-3p inhibitor, and miR-506-3p inhibitor+shBMP7. C–F ALP activity, ALP staining, ARS staining, and CCK-8 assays showed the ALP activity and viability of hBMSCs transfected with NC inhibitor, miR-506-3p inhibitor, and miR-506-3p inhibitor+shBMP7. *P < 0.05

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X