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Fig. 3 | Journal of Orthopaedic Surgery and Research

Fig. 3

From: FGD5-AS1 facilitates the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells via targeting the miR-506-3p/BMP7 axis

Fig. 3

miR-506-3p is a direct target of FGD5-AS1. A Binding sequences between FGD5-AS1 and miR-506-3p were predicted by the starBase website. B Dual-luciferase reporter assay showed the luciferase activity of FGD5-AS1-WT or FGD5-AS1-MUT in hBMSCs transfected with NC mimics or miR-506-3p mimics. C RT-qPCR analysis was used to detect the expression of miR-506-3p in hBMSCs transfected with shFGD5-AS1. D RT-qPCR analysis showed the FGD5-AS1 expression in hBMSCs transfected with miR-506-3p mimics. *P < 0.05

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