Fig. 6
From: Hsa_circ_0004674 promotes osteosarcoma doxorubicin resistance by regulating the miR-342-3p/FBN1 axis
MiR-342-3p regulated OS DXR resistance by targeting FBN1. A-B MiR-342-3p and FBN1 expression was measured using qRT-PCR and WB analysis, respectively. C WB analysis was used to test FBN1 protein. D CCK8 assay was performed to detect the DXR resistance of cells. Colony formation assay (E) and flow cytometry (F-G) were used to analyze the number of colonies, cell cycle process and apoptosis rate. H The p-gp and MCL-1 protein levels were examined using WB analysis. *P < 0.05