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Fig. 6 | Journal of Orthopaedic Surgery and Research

Fig. 6

From: Circ_0025908 regulates cell vitality and proliferation via miR-137/HIPK2 axis of rheumatic arthritis

Fig. 6

MiR-137 regulated the progression of RA by targeting HIPK2. (A and B) The level of HIPK2 expression was detected by qRT-PCR and western blot. (C) The cell viability, (D) the rate of EdU positive cells, (E) the cell mitotic cycle, (F) the protein level of Ki67 and PCNA, (G) the rate of apoptosis, (H) the protein level of Bax and Bcl-2, (I-K) the level of IL-1β, IL-6, and TNF-α, (L) the protein level of p-NF-KB p65 and total-NF-KB p65 were examined by CCK8 assay, EdU assay, flow cytometry assay, ELISA, and western blot, respectively. *P < 0.05

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