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Fig. 4 | Journal of Orthopaedic Surgery and Research

Fig. 4

From: Biomarker potential of lncRNA GNAS-AS1 in osteosarcoma prognosis and effect on cellular function

Fig. 4

miR-490-3p was downstream miRNA of lncRNA GNAS-AS1. A Binding sites for lncRNA GNAS-AS1 in the miR-490-3p 3′UTR were predicted using lncRNASNP2. B Expression of lncRNA GNAS-AS1 and miR-490-3p is negatively correlated. C Expression of miR-490-3p was raised when lncRNA GNAS-AS1 was inhibited. D pLHCX retroviral vector with wild-type lncRNA GNAS-AS1 (WT-GNAS-AS1) and mutated one (MUT-GNAS-AS1) were constructed, and co-transfected into MG-63 cells with the miR-490-3p mimic or inhibitor. The relative luciferase activity was measured. **P < 0.01, ***P < 0.001

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