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Table 1 Patient characteristics between clinicopathological variables and stainability of KIAA1199 and HABP

From: Overexpression of KIAA1199, a novel strong hyaluronidase, is a poor prognostic factor in patients with osteosarcoma

   KIAA1199   HABP  
All patients (n = 49) High (n = 34) Low (n = 15) P value High (n = 21) Low (n = 28) P value
Gender Male 30 Female 19 Male 21 Female 13 Male 9 Female 6 0.91 Male 11 Female 10 Male 19 Female 9 0.27
Age (years) 23.1 (7-74) 24.3 20.3 0.49 24.1 22.3 0.75
Size (cm) 11.5 (4-26) 11.1 12.2 0.57 12.8 10.5 0.16
Location     0.91    0.76
 Pelvis 3 2 1   2 1  
 Humerus 3 2 1   1 2  
 Femur 19 12 7   9 10  
 Tibia 23 17 6   9 14  
 Trunk 1 1 0   0 1  
Histology     0.51    0.17
 Osteoblastic 23 17 6   7 16  
 Fibroblastic 13 7 6   6 7  
 Chondroblastic 12 9 3   8 4  
 Telangiectatic 1 1 0   0 1  
Metastasis        
 All 27 24 3 0.002 13 14 0.3
 Exists at initial diagnosis 10 9 1 0.11 3 7 0.36
AJCC classification (8th edition)     0.21    0.79
 IIA 14 9 5   4 10  
 IIB 24 16 8   13 11  
 IV 10 9 1   3 7  
 Unknown 1 0 1   1 0  
Necrosis rate (%) 67.4 (15-100) (unknown 9) 59 84.8 0.003 77.5 61.2 0.09
HABP positivity (%) 61.7 (14.4-99.6) 61.7 61.8 0.99
KIAA1199 positivity (%) 76.8 (16.2-97.3) 75.3 77.9 0.65