|  | KIAA1199 |  | HABP |  | ||
---|---|---|---|---|---|---|---|
All patients (n = 49) | High (n = 34) | Low (n = 15) | P value | High (n = 21) | Low (n = 28) | P value | |
Gender | Male 30 Female 19 | Male 21 Female 13 | Male 9 Female 6 | 0.91 | Male 11 Female 10 | Male 19 Female 9 | 0.27 |
Age (years) | 23.1 (7-74) | 24.3 | 20.3 | 0.49 | 24.1 | 22.3 | 0.75 |
Size (cm) | 11.5 (4-26) | 11.1 | 12.2 | 0.57 | 12.8 | 10.5 | 0.16 |
Location | Â | Â | Â | 0.91 | Â | Â | 0.76 |
 Pelvis | 3 | 2 | 1 |  | 2 | 1 |  |
 Humerus | 3 | 2 | 1 |  | 1 | 2 |  |
 Femur | 19 | 12 | 7 |  | 9 | 10 |  |
 Tibia | 23 | 17 | 6 |  | 9 | 14 |  |
 Trunk | 1 | 1 | 0 |  | 0 | 1 |  |
Histology | Â | Â | Â | 0.51 | Â | Â | 0.17 |
 Osteoblastic | 23 | 17 | 6 |  | 7 | 16 |  |
 Fibroblastic | 13 | 7 | 6 |  | 6 | 7 |  |
 Chondroblastic | 12 | 9 | 3 |  | 8 | 4 |  |
 Telangiectatic | 1 | 1 | 0 |  | 0 | 1 |  |
Metastasis | Â | Â | Â | Â | Â | Â | Â |
 All | 27 | 24 | 3 | 0.002 | 13 | 14 | 0.3 |
 Exists at initial diagnosis | 10 | 9 | 1 | 0.11 | 3 | 7 | 0.36 |
AJCC classification (8th edition) | Â | Â | Â | 0.21 | Â | Â | 0.79 |
 IIA | 14 | 9 | 5 |  | 4 | 10 |  |
 IIB | 24 | 16 | 8 |  | 13 | 11 |  |
 IV | 10 | 9 | 1 |  | 3 | 7 |  |
 Unknown | 1 | 0 | 1 |  | 1 | 0 |  |
Necrosis rate (%) | 67.4 (15-100) (unknown 9) | 59 | 84.8 | 0.003 | 77.5 | 61.2 | 0.09 |
HABP positivity (%) | 61.7 (14.4-99.6) | 61.7 | 61.8 | 0.99 | ― | ― | ― |
KIAA1199 positivity (%) | 76.8 (16.2-97.3) | ― | ― | ― | 75.3 | 77.9 | 0.65 |