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Table 1 Patient characteristics between clinicopathological variables and stainability of KIAA1199 and HABP

From: Overexpression of KIAA1199, a novel strong hyaluronidase, is a poor prognostic factor in patients with osteosarcoma

  

KIAA1199

 

HABP

 

All patients (n = 49)

High (n = 34)

Low (n = 15)

P value

High (n = 21)

Low (n = 28)

P value

Gender

Male 30 Female 19

Male 21 Female 13

Male 9 Female 6

0.91

Male 11 Female 10

Male 19 Female 9

0.27

Age (years)

23.1 (7-74)

24.3

20.3

0.49

24.1

22.3

0.75

Size (cm)

11.5 (4-26)

11.1

12.2

0.57

12.8

10.5

0.16

Location

   

0.91

  

0.76

 Pelvis

3

2

1

 

2

1

 

 Humerus

3

2

1

 

1

2

 

 Femur

19

12

7

 

9

10

 

 Tibia

23

17

6

 

9

14

 

 Trunk

1

1

0

 

0

1

 

Histology

   

0.51

  

0.17

 Osteoblastic

23

17

6

 

7

16

 

 Fibroblastic

13

7

6

 

6

7

 

 Chondroblastic

12

9

3

 

8

4

 

 Telangiectatic

1

1

0

 

0

1

 

Metastasis

       

 All

27

24

3

0.002

13

14

0.3

 Exists at initial diagnosis

10

9

1

0.11

3

7

0.36

AJCC classification (8th edition)

   

0.21

  

0.79

 IIA

14

9

5

 

4

10

 

 IIB

24

16

8

 

13

11

 

 IV

10

9

1

 

3

7

 

 Unknown

1

0

1

 

1

0

 

Necrosis rate (%)

67.4 (15-100) (unknown 9)

59

84.8

0.003

77.5

61.2

0.09

HABP positivity (%)

61.7 (14.4-99.6)

61.7

61.8

0.99

―

―

―

KIAA1199 positivity (%)

76.8 (16.2-97.3)

―

―

―

75.3

77.9

0.65