Outcomes | Trials, n | Patients, n | Effect size (95% CI) | P value | I2 (%) | Quality of the evidence (GRADE) | |
---|---|---|---|---|---|---|---|
FIB | Control | ||||||
Postoperative pain at 0-2 h | 6 | 199 | 199 | −0.06 (−0.44, 0.32) | 0.76 | 71 | ⨁⨁⊝⊝ lowab |
Postoperative pain at 6 h | 6 | 219 | 221 | 0.22 (−0.21, 0.65) | 0.32 | 79 | ⨁⨁⊝⊝ lowab |
Postoperative pain at 12 h | 7 | 259 | 261 | 0.14 (−0.48, 0.76) | 0.65 | 91 | ⨁⨁⊝⊝ lowab |
Postoperative pain at 24 h | 12 | 407 | 408 | 0.11 (−0.36, 0.58) | 0.64 | 90 | ⨁⨁⨁⊝ moderatea |
Postoperative opioid consumption during the first 24 h | 10 | 328 | 328 | −0.53 (−1.23, 0.18) | 0.14 | 94 | ⨁⨁⨁⊝ moderatea |
Postoperative opioid consumption during the first 48 h | 5 | 218 | 220 | −0.62 (−1.85, 0.62) | 0.33 | 97 | ⨁⨁⊝⊝ lowab |
Complications | 9 | 328 | 330 | 0.99 (0.58, 1.72) | 0.99 | 73 | ⨁⨁⨁⊝ moderatea |