Fig. 6
From: MiR-330-5p inhibits intervertebral disk degeneration via targeting CILP
Influence of CILP on the senescence and ECM production of NP cells. MiR-330-5p mimic and/or pcDNA-CILP was transfected into the TNF-α-treated NP cells. (A) β-galactosidase staining was applied to analyze NP cell senescence. MiR-330-5p mimic and/or pcDNA-CILP was transfected into NP cells. (B) qRT-PCR was applied to quantify ACAN, COL1A1, COL2A1, MMP-3, and MMP-9 expressions in NP cells. **P < 0.01 vs. control. #P < 0.05 vs. TNF-α or miR-330-5p mimic. ##P < 0.01 vs. miR-330-5p mimic. $$P < 0.01 vs. TNF-α + miR-330-5p mimic of three independent experiments