Fig. 1

Tibial bone tissue stained with HE observed under microscope. HE hematoxylin and eosin. A, D, and F present samples from the EG, and G shows samples from the CG. Figures B and C are enlargements of b and c in A; E is an enlargement of e in D; H is the enlarged image of h in G. A, B, and C strong neutrophil, plasma cell, lymphocyte, multinucleated giant cell, and pus cell infiltration in the tibial bone marrow cavity; D and E formation of bone abscess in the metaphysis and formation of a large number of neutrophils, plasma cells, lymphocytes, multinuclear giant cells, and abscess focus in the EG. F inflammatory infiltration, bone erosion and destruction in the EG; G and H the hemopoietic cells and adipocytes in the bone marrow cavity are arranged regularly, and there is no obvious sign of infection in the CG (A, D, and G: × 20; B, C, E, F, and H: × 400). EG, experimental group; CG, control group