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Fig. 6 | Journal of Orthopaedic Surgery and Research

Fig. 6

From: Study on the potential active components and molecular mechanism of Xiao Huoluo Pills in the treatment of cartilage degeneration of knee osteoarthritis based on bioinformatics analysis and molecular docking technology

Fig. 6

GO and KEGG enrichment analyses of 33 candidate targets. A Three types of GO terms for target genes and gene products. B The Bubble chart of the top 20 terms extracted according to the p.adjust value based on GO enrichment analysis. C The Bar chart of the top 20 terms extracted according to the p.adjust value based on GO enrichment analysis. D The Bubble chart of the top 20 pathways extracted according to the p.adjust value based on KEGG enrichment analysis. E The Bar graph of the top 20 pathways extracted according to the p.adjust value based on KEGG enrichment analysis. F Top 5 significantly enriched BP, CC, and MF categories based on gene ontology, and the Top 8 significantly enriched BP, CC, and MF categories. G TNF signaling pathway map of KOA targets treated with XHLP. H PI3K-Akt signaling pathway map of KOA targets treated with XHLP. (the red nodes represent the most potential targets, arrows represent the activation effect, T arrows represent the inhibition effect, and segments show the activation effect or inhibition effect)

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X