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Table 5 Haplotype-based association analyses in the study

From: The effect of common variants in GDF5 gene on the susceptibility to chronic postsurgical pain

Haplotype Estimated frequencies (%) Global P value**
  Case Control P value*
rs143384-rs224335-rs739329 < 0.000001
 AGG 80.27 75.95 0.00012
 GGG 11.61 15.24 0.00010
 GAA 3.78 4.48 0.19540
 GAG 3.32 3.88 0.26244
  1. Significant P values are in bold italics. Haplotypes are not shown, if frequency less than 1%
  2. *Means based on 100,000 permutations
  3. **Means based on comparison of frequency distribution of all haplotypes