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Table 2 Multiple comparisons for correlation between GDF gene SNP rs143384 and CPSP risk

From: The effect of common variants in GDF5 gene on the susceptibility to chronic postsurgical pain

  Case (n = 1048) Control (n = 2062) P*
Gender: male
 GG 20 (1.91%) 63 (3.06%) 0.06
 GA/AA 560 (53.43%) 1079 (52.32%)  
Female
 GG 14 (1.34%) 46 (2.23%) 0.08
 GA/AA 454 (43.32%) 874 (42.39%)  
Age: ≤ 61 years
 GG 12 (1.15%) 48 (2.33%) 0.02
 GA/AA 432 (41.22%) 816 (39.57%)  
> 61 years
 GG 22 (2.10%) 61 (2.96%) 0.17
 GA/AA 582 (55.53%) 1137 (55.14%)  
BMI: ≤ 26
 GG 15 (1.43%) 56 (2.72%) 0.02
 GA/AA 464 (44.27%) 854 (41.42%)  
> 26
 GG 19 (1.81%) 53 (2.57%) 0.22
 GA/AA 550 (52.48%) 1099 (53.30%)  
Lifestyle: smoking
 GG 8 (0.76%) 29 (1.41%) 0.14
 GA/AA 242 (23.09%) 485 (23.52%)  
No-smoking
 GG 26 (2.48%) 80 (3.88%) 0.03
 GA/AA 772 (73.66%) 1468 (71.19%)  
Drinking
 GG 8 (0.76%) 37 (1.79%) 0.03
 GA/AA 303 (28.91%) 605 (29.34%)  
No-drinking
 GG 26 (2.48%) 72 (3.49%) 0.13
 GA/AA 711 (67.84%) 1348 (65.37%)  
Prior pain history
 GG 2 (0.19%) 9 (0.44%) 0.24
 GA/AA 116 (11.07%) 211 (10.23%)  
No prior pain history
 GG 32 (3.05%) 100 (4.85%) 0.02
 GA/AA 898 (85.69%) 1742 (84.48%)  
  1. *P value was calculated by chi-square test; the significant value was shown in bold italics