Table 2 Multiple comparisons for correlation between GDF gene SNP rs143384 and CPSP risk
From: The effect of common variants in GDF5 gene on the susceptibility to chronic postsurgical pain
Case (n = 1048) | Control (n = 2062) | P* | |
|---|---|---|---|
Gender: male | |||
GG | 20 (1.91%) | 63 (3.06%) | 0.06 |
GA/AA | 560 (53.43%) | 1079 (52.32%) | |
Female | |||
GG | 14 (1.34%) | 46 (2.23%) | 0.08 |
GA/AA | 454 (43.32%) | 874 (42.39%) | |
Age: ≤ 61 years | |||
GG | 12 (1.15%) | 48 (2.33%) | 0.02 |
GA/AA | 432 (41.22%) | 816 (39.57%) | |
> 61 years | |||
GG | 22 (2.10%) | 61 (2.96%) | 0.17 |
GA/AA | 582 (55.53%) | 1137 (55.14%) | |
BMI: ≤ 26 | |||
GG | 15 (1.43%) | 56 (2.72%) | 0.02 |
GA/AA | 464 (44.27%) | 854 (41.42%) | |
> 26 | |||
GG | 19 (1.81%) | 53 (2.57%) | 0.22 |
GA/AA | 550 (52.48%) | 1099 (53.30%) | |
Lifestyle: smoking | |||
GG | 8 (0.76%) | 29 (1.41%) | 0.14 |
GA/AA | 242 (23.09%) | 485 (23.52%) | |
No-smoking | |||
GG | 26 (2.48%) | 80 (3.88%) | 0.03 |
GA/AA | 772 (73.66%) | 1468 (71.19%) | |
Drinking | |||
GG | 8 (0.76%) | 37 (1.79%) | 0.03 |
GA/AA | 303 (28.91%) | 605 (29.34%) | |
No-drinking | |||
GG | 26 (2.48%) | 72 (3.49%) | 0.13 |
GA/AA | 711 (67.84%) | 1348 (65.37%) | |
Prior pain history | |||
GG | 2 (0.19%) | 9 (0.44%) | 0.24 |
GA/AA | 116 (11.07%) | 211 (10.23%) | |
No prior pain history | |||
GG | 32 (3.05%) | 100 (4.85%) | 0.02 |
GA/AA | 898 (85.69%) | 1742 (84.48%) | |