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Fig. 5 | Journal of Orthopaedic Surgery and Research

Fig. 5

From: LncRNA CASC19 accelerates chondrocytes apoptosis and proinflammatory cytokine production to exacerbate osteoarthritis development through regulating the miR-152-3p/DDX6 axis

Fig. 5

CASC19 regulated proinflammatory cytokine production and cell apoptosis through DDX6. Groups were divided into the IL-1β+sh-NC, IL-1β+sh-CASC19, and IL-1β+sh-CASC19+oe-DDX6 group. a The overexpression efficiency of DDX6 was notarized through RT-qPCR assay. bd The IL-6, IL-8, and TNF-α levels were tested through ELISA assay. e The cell viability was assessed through CCK-8 assay. f The cell apoptosis was examined through flow cytometry assay. *P < 0.05 and **P < 0.01

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