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Fig. 3 | Journal of Orthopaedic Surgery and Research

Fig. 3

From: LncRNA CASC19 accelerates chondrocytes apoptosis and proinflammatory cytokine production to exacerbate osteoarthritis development through regulating the miR-152-3p/DDX6 axis

Fig. 3

MiR-152-3p was a sponge for CASC19. a The miRNAs sponged with CASC19 were predicted through starBase website with the condition of CLIP Data: high stringency (≥ 3). The binding ability between CASC19 and miRNAs was tested by RNA pull-down assay. b The miR-152-3p expression was verified through RT-qPCR assay. c The overexpression efficiency of miR-152-3p was identified through RT-qPCR assay. d The binding ability between CASC19 and miR-152-3p was confirmed through luciferase reporter assay. e The binding ability between CASC19 and miR-152-3p was assessed through RIP assay. *P < 0.05, **P < 0.01, and ***P < 0.001

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