Fig. 7

Inhibition of miR-195 attenuated the progression of IVDD in a puncture-induced rat model. A Radiographs of X-ray were obtained at 4 weeks post-surgery (the white arrow: location of the needle-puncture disc). B The changes in disc height index (DHI) were determined in different groups at 4 weeks post-surgery. C Representative HE and TUNEL staining of disc samples from different experimental groups at 4 weeks post-surgery were shown; blue fluorescence indicating total cells; green fluorescence indicating TUNEL-positive cells. D, E The histology score (D) and NP cell apoptosis rates (E) evaluated at 4 weeks post-surgery in different groups; *P < 0.05 compared with sham group; ^#P < 0.05 compared with punctured group