Fig. 3
From: NDRG1 regulates osteosarcoma cells via mediating the mitochondrial function and CSCs differentiation
NDRG1 expression maintained the CSCs stemness. (A) STRING was used to predict interaction between NDRG and SOX2. (B) Tumor-formation assay for CD133+ positive cells. (C) The expression of NDRG1 in different cell lines. (D) NDRG1 siRNA downregulated NDRG1 in CSCs. (E) Silencing of NDRG1 reduced the pluripotency of CSCs. (F) Downregulation of NDRG1 promoted CSCs differentiation