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Table 4 The association between the coagulation profile and treatment outcomes of two-staged arthroplasty. Corresponding cut-off and predictive values

From: The change of coagulation profile in two-staged arthroplasty for periprosthetic joint infection patients: a retrospective cohort study

 

AUC (95% CI)

Yonden index

Optimal cut-off

Sensitivity

specificity

The coagulation profile before reimplantation

APTT

0.526(0.377,0.674)

0.170

33.45

92.9

24.1

PT

0.608(0.454,0.762)

0.3

13.15

58.6

28.6

TT

0.482(0.29,0.674)

0.158

16.05

57.1

41.4

D-dimer

0.542(0.359,0.725)

0.262

1.19

66.2

60

Platelet count

0.560(0.417,0.702)

0.188

231.5

33

85.7

INR

0.632(0.479,0.786)

0.335

1.005

62.1

71.4

ESR

0.465(0.282,0.647)

0.083

31

8.3

100

CRP

0.615(0.427,0.803)

0.318

0.33

81.8

50

Combined coagulation profile

0.667(0.511,0.823)

NA

NA

NA

NA

The change of coagulation profile from preresection to preimplantation

APTT

0.546 (0.378, 0.714)

0.145

-3.8

78.6

21.4

PT

0.545 (0.392, 0.699)

0.175

0.95

18.3

81.7

TT

0.493 (0.327, 0.659)

0.096

2.5

10

100

D-dimer

0.611 (0.403, 0.819)

0.278

-0.395

70.7

57.1

Platelet count

0.528 (0.374, 0.682)

0.248

56.5

63.3

61.5

INR

0.626 (0.488, 0.765)

0.235

0.05

57.1

66.4

Plasma fibrinogen

0.549 (0.363, 0.736)

0.227

0.365

79.8

57.1

Combined coagulation profile

0.667 (0.526, 0.808)

NA

NA

NA

NA