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Fig. 2 | Journal of Orthopaedic Surgery and Research

Fig. 2

From: miR-520c-3p regulates IL-1β-stimulated human chondrocyte apoptosis and cartilage degradation by targeting GAS2

Fig. 2

Protective role miR-520c-3p in alleviating IL-1β induced the apoptosis, inflammation response, and matrix degradation of chondrocytes. a qRT-PCR to assess the mRNA levels of caspase-3, Bcl-2, MMP-13, COL2A1, IL-6, and IL-8 in control, IL-1β, IL-1β + NC mimic, and IL-1β + miR-520c-3p mimic groups. b Western blot assay to evaluate the protein levels of cleaved-caspase-3, Bcl-2, MMP-13, COL2A1, IL-6, and IL-8 in control, IL-1β, IL-1β + NC mimic, and IL-1β + miR-520c-3p mimic groups

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