Table 6 Comparison of clinical characteristics among subjects with different genotypes at rs201335371 of SOX4 gene
From: The effect of SOX4 gene 3′UTR polymorphisms on osteoporosis
CC(n = 307) | CT(n = 250) | TT(n = 103) | P | |
|---|---|---|---|---|
Age(years, mean ± SD) | 65.07 ± 9.74 | 64.87 ± 9.77 | 67.52 ± 10.11 | 0.06 |
Gender [n(%)] | 0.64 | |||
Male | 151(49.19%) | 129(51.60%) | 56(54.37%) | |
Female | 156(50.81%) | 121(48.40%) | 47(45.63%) | |
BMI(kg/m2, mean ± SD) | 22.65 ± 2.20 | 22.84 ± 2.25 | 22.68 ± 2.16 | 0.62 |
Smoking | 0.62 | |||
Yes | 108(35.18%) | 87(34.80%) | 31(30.10%) | |
No | 199(64.82%) | 163(65.20%) | 72(69.90%) | |
Drinking | 0.38 | |||
Yes | 118(38.44%) | 86(34.40%) | 43(41.75%) | |
No | 189(61.56%) | 164(65.60%) | 60(58.25%) | |
BMD(g/m2) | 0.83 ± 0.23 | 0.89 ± 0.22 | 0.95 ± 0.27 | < 0.01 |
T-score | − 1.92 ± 1.83 | − 1.20 ± 1.80 | − 1.13 ± 1.83 | < 0.01 |
Z-score | − 2.50 ± 1.51 | − 2.19 ± 1.50 | − 2.05 ± 1.14 | < 0.01 |