Table 5 Comparison of clinical characteristics among subjects with different genotypes at rs139085828 of SOX4 gene
From: The effect of SOX4 gene 3′UTR polymorphisms on osteoporosis
GG(n = 595) | GA(n = 44) | AA(n = 21) | P | |
|---|---|---|---|---|
Age(years, mean ± SD) | 65.53 ± 9.82 | 63.07 ± 9.24 | 65.81 ± 11.38 | 0.27 |
Gender [n(%)] | 0.84 | |||
Male | 302(50.76%) | 22(50.00%) | 12(57.14%) | |
Female | 293(49.24%) | 22(50.00%) | 9(42.86%) | |
BMI(kg/m2, mean ± SD) | 22.76 ± 2.23 | 22.53 ± 2.08 | 22.19 ± 2.14 | 0.43 |
Smoking | 0.82 | |||
Yes | 204(34.29%) | 16(36.36%) | 6(28.57%) | |
No | 391(65.71%) | 28(63.64%) | 15(71.43%) | |
Drinking | 0.35 | |||
Yes | 220(36.97%) | 17(38.64%) | 11(52.38%) | |
No | 375(63.03%) | 27(61.36%) | 10(47.62%) | |
BMD(g/m2) | 0.88 ± 0.24 | 0.78 ± 0.20 | 0.73 ± 0.15 | < 0.01 |
T-score | − 1.42 ± 1.84 | − 2.15 ± 1.84 | − 3.15 ± 1.02 | < 0.01 |
Z-score | − 2.25 ± 1.44 | − 2.57 ± 1.58 | − 3.50 ± 1.43 | < 0.01 |