Table 4 Comparison of clinical characteristics among subjects with different genotypes at rs79958549 of SOX4 gene
From: The effect of SOX4 gene 3′UTR polymorphisms on osteoporosis
GG(n = 577) | GA(n = 56) | AA(n = 27) | P值 | |
|---|---|---|---|---|
Age(years, mean ± SD) | 65.51 ± 9.80 | 63.98 ± 10.35 | 65.44 ± 9.81 | 0.54 |
Gender [n(%)] | 0.19 | |||
Male | 300(51.99%) | 22(39.29%) | 14(51.85%) | |
Female | 277(48.01%) | 34(60.71%) | 13(48.15%) | |
BMI(kg/m2, mean ± SD) | 22.77 ± 2.21 | 22.68 ± 2.15 | 21.99 ± 2.48 | 0.20 |
Smoking | 0.12 | |||
Yes | 190(32.93%) | 26(46.43%) | 10(37.04%) | |
No | 387(67.07%) | 30(53.57%) | 17(62.96%) | |
Drinking | 0.13 | |||
Yes | 213(36.92%) | 19(33.93%) | 15(55.56%) | |
No | 364(63.08%) | 37(66.07%) | 12(44.44%) | |
BMD(g/m2) | 0.88 ± 0.24 | 0.77 ± 0.17 | 0.74 ± 0.14 | < 0.01 |
T-score | − 1.38 ± 1.84 | − 1.61 ± 1.87 | − 3.09 ± 0.88 | < 0.01 |
Z-score | − 2.19 ± 1.39 | − 3.23 ± 1.82 | − 3.00 ± 1.37 | < 0.01 |