Table 1 Demographic and clinical characteristics of OP patients, OA patients and healthy CTRs
OP (n=32) | OA (n=19) | CTRs (n=25) | T test (Mann-Whitney test) | |
|---|---|---|---|---|
Age (years) | 77.65 ± 11.19 | 71.95 ± 5.80 | 43.68 ± 13.32 | OP vs CTRL **** (P < 0.0001); OA vs CTRL **** (P < 0.0001) |
BMI (kg/m2) | 25.99 ± 4.61 | 28.85 ± 5.41 | 24.17 ± 3.58 | OP vs CTRL ns (P = 0.370); OA vs CTRL ** (P = 0.004) |
BMD L1–L4 | 0.94 ± 0.18 | 1.35 ± 0.19 | 1.26 ± 0.15 | OP vs CTRL **** (P < 0.0001); OA vs CTRL ns (P = 0.303) |
t-score L1–L4 | − 1.99 ± 1.37 | 1.56 ± 1.61 | 0.78 ± 1.11 | OP vs CTRL **** (P < 0.0001); OA vs CTRL ns (P = 0.290) |
BMD FN | 0.75 ± 0.13 | 1.02 ± 0.18 | 0.93 ± 0.09 | OP vs CTRL *** (P < 0.001); OA vs CTRL ns (P = 0.321) |
t-score FN | − 2.15 ± 0.80 | − 0.02 ± 1.35 | − 0.63 ± 0.68 | OP vs CTRL **** (P < 0.0001); OA vs CTRL ns (P = 0.485) |
Calcium (mg/dl) | 8.99 ± 0.44 | 8.55 ± 0.34 | 9.27 ± 0.61 | OP vs CTRL ns (P = 0.186); OA vs CTRL ** (P = 0.003) |
Phosphorus (mg/dl) | 3.07 ± 0.68 | – | 3.27 ± 0.69 | OP vs CTRL ns (P = 0.419) |
PTH (pg/ml) | 122.38 ± 91.34 | 84.84 ± 29.63 | 58.57 ± 24.22 | OP vs CTRL ** (P = 0.026); OA vs CTRL ns (P = 0.061) |
25-(OH)-Vit D (ng/ml) | 15.99 ± 15.28 | 17.16 ± 7.39 | 24.81 ± 15.58 | OP vs CTRL * (P = 0.013); OA vs CTRL ns (P = 0.148) |
ALP (U/l) | 80.52 ± 20.79 | 69.37 ± 16.71 | 72.33 ± 12.49 | OP vs CTRL ns (P = 0.275); OA vs CTRL ns (P = 0.490) |