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Fig. 3 | Journal of Orthopaedic Surgery and Research

Fig. 3

From: Blocking circ-CNST suppresses malignant behaviors of osteosarcoma cells and inhibits glycolysis through circ-CNST-miR-578-LDHA/PDK1 ceRNA networks

Fig. 3

Role of circ-CNST deficiency in cell growth of OS cells in vivo. a RT-qPCR detected relative circ-CNST expression in U2OS cells stably transfected with sh-circ-CNST comparing to sh-NC-transfected cells. b, c Transfected U2OS cells were inoculated in nude mice, and 8 mice were set in each group. b Tumor volume was calculated at indicated time-points. c Tumor weight was measured on the last day. d RT-qPCR detected relative circ-CNST expression in tissues from xenograft tumors. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001

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