Table 2 The top six pathways in GO and KEGG enrichment analyses of the 72 genes related to both autophagy and LDD

GOTERM_BP_FAT

GO:0042127~regulation of cell proliferation

46

2.12E−30

GOTERM_BP_FAT

GO:0010562~positive regulation of phosphorus metabolic process

40

1.70E−29

GOTERM_BP_FAT

GO:0045937~positive regulation of phosphate metabolic process

40

1.70E−29

GOTERM_BP_FAT

GO:0008219~cell death

48

1.79E−28

GOTERM_BP_FAT

GO:0042981~regulation of apoptotic process

43

1.85E−28

GOTERM_BP_FAT

GO:0010941~regulation of cell death

44

2.20E−28

GOTERM_CC_FAT

GO:0005615~extracellular space

37

5.19E−19

GOTERM_CC_FAT

GO:0044421~extracellular region part

44

2.75E−10

GOTERM_CC_FAT

GO:0005576~extracellular region

47

1.36E−09

GOTERM_CC_FAT

GO:0005578~proteinaceous extracellular matrix

14

1.01E−08

GOTERM_CC_FAT

GO:0009986~cell surface

18

5.52E−08

GOTERM_CC_FAT

GO:0031012~extracellular matrix

15

1.25E−07

GOTERM_MF_FAT

GO:0005125~cytokine activity

20

7.59E−20

GOTERM_MF_FAT

GO:0005102~receptor binding

36

1.05E−18

GOTERM_MF_FAT

GO:0005126~cytokine receptor binding

20

3.81E−18

GOTERM_MF_FAT

GO:0008083~growth factor activity

13

5.03E−12

GOTERM_MF_FAT

GO:0042802~identical protein binding

23

3.69E−08

GOTERM_MF_FAT

GO:0019838~growth factor binding

9

8.56E−08

KEGG_PATHWAY

hsa04060:Cytokine-cytokine receptor interaction

22

3.02E−16

KEGG_PATHWAY

hsa05200:Pathways in cancer

24

4.51E−14

KEGG_PATHWAY

hsa05161:Hepatitis B

16

8.20E−13

KEGG_PATHWAY

hsa04210:Apoptosis

12

3.07E−12

KEGG_PATHWAY

hsa04668:TNF signaling pathway

14

4.18E−12

KEGG_PATHWAY

hsa04066:HIF-1 signaling pathway

13

2.18E−11