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Fig. 6 | Journal of Orthopaedic Surgery and Research

Fig. 6

From: Circ_0116061 regulated the proliferation, apoptosis, and inflammation of osteoarthritis chondrocytes through regulating the miR-200b-3p/SMURF2 axis

Fig. 6

SMURF2 knockdown regulated the biological functions of OA chondrocytes. OA chondrocytes were transfected with si-NC or si-SMURF2. a WB analysis was performed to test the protein expression of SMURF2. CCK8 assay (b), colony formation assay (c), and flow cytometry (d) were used to determine the cell viability, the cell cloning number, and apoptosis rate. e–n WB analysis was employed to test the protein levels of Cyclin D1, Bcl2, Bax, Cleaved-casp3, IL-1β, IL-6, IL-1α, and TNFα. ***P < 0.001

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X