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Fig. 2 | Journal of Orthopaedic Surgery and Research

Fig. 2

From: Circ_0116061 regulated the proliferation, apoptosis, and inflammation of osteoarthritis chondrocytes through regulating the miR-200b-3p/SMURF2 axis

Fig. 2

Silencing of circ_0116061 regulated the biological functions of OA chondrocytes. OA chondrocytes were transfected with si-NC or si-circ_0116061. a The expression of circ_0116061 was detected by qRT-PCR. CCK8 assay (b), colony formation assay (c), and flow cytometry (d) were used to test cell viability, the cell cloning number, and apoptosis rate. e–n The protein levels of Cyclin D1, Bcl2, Bax, Cleaved-casp3, IL-1β, IL-6, IL-1α, and TNFα were determined by WB analysis. ***P < 0.001

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X