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Table 1 Characteristics of included studies and population

From: Nonoperative treatment of insertional Achilles tendinopathy: a systematic review

No.

Study

Year

LOE

Study design

Country

No. of patients (tendons)

Activity level

Age (year)

Duration of symptoms (month)

Diagnosis

1

Fahlström et al.

2003

4

Prospective

Sweden

30 (31)

Recreational

37.9

32

CE, US, MRI, X-ray

2

Öhberg et al.

2003

4

Pilot study

Sweden

11 (11)

Mixed

44

29

CE, US

3

Costantino et al.

2005

3

Retrospective

Italy

Group A 5 (5)

Professional

32.7

≥ 2

CE, US

      

Group B 5 (5)

Professional

32.7

≥ 2

 
      

Group C 5 (5)

Professional

32.7

≥ 2

 

4

Furia et al.

2006

3

Retrospective

USA

Group A 35 (35)

Mixed

50

19.9

CE, MRI, X-ray

      

Group B 33 (33)

Mixed

52.6

16.8

 

5

Knobloch et al.

2007

4

Prospective

Germany

10 (10)

Recreational

NR

≥ 3

CE, US

6

Rompe et al.

2008

1

RCT

Germany

25 (30)

Mixed

39.2

24.8

CE, US, X-ray

      

25 (31)

Mixed

40.4

26.3

 

7

Jonsson et al.

2008

4

Pilot study

Sweden

27 (34)

Recreational

53.4

26.5

CE, US

8

Ryan et al.

2010

4

Case series

Canada

NR (22)

NR

NR

≥ 6

CE, US

9

Verrall et al.

2011

4

Retrospective

Australia

14 (14)

Professional

NR

4.5

CE

10

Saxena et al.

2011

2

Prospective

USA

NR (19)

NR

54.3

NR

CE, MRI, X-ray

11

Notarnicola et al.

2012

1

RCT

Italy

Group A 32 (32)

NR

NR

6

CE, US, MRI, X-ray

      

Group B 32 (32)

NR

NR

6

 

12

Notarnicola et al.

2013

2

RCT

Italy

Group A 30 (30)

NR

57.5

≥ 6

CE, US, MRI, X-ray

      

Group B 30 (30)

NR

59.5

≥ 6

 

13

Kedia et al.

2014

2

RCT

USA

Group A 16 (19)

Mixed

51.7

18.5

CE

      

Group B 20 (20)

Mixed

55.3

18.3

 

14

McCormack et al.

2016

2

RCT

USA

Group A 6 (6)

NR

53.3

21.9

CE

      

Group B 6 (6)

NR

53.9

20.8

 

15

Taylor et al.

2016

4

Prospective

UK

12 (12)

NR

54

42

CE, US

16

Pavone et al.

2016

4

Case series

Italy

40 (40)

NR

41

≥ 3

CE, X-ray

17

Wu et al.

2016

3

Retrospective

China

Group A 37 (37)

NR

37.6

≥ 6

CE, X-ray

      

Group B 30 (30)

NR

35.8

≥ 6

 

18

Erroi et al.

2017

3

Retrospective

Italy

Group A 24 (24)

Mixed

53.2

13.7

CE, US

      

Group B 21 (21)

Mixed

47.7

14.3

 

19

Maffulli et al.

2018

4

Case series

UK

80 (80)

NR

53.4

NR

CE

20

Wheeler et al.

2019

4

Case series

UK

30 (30)

NR

55.4

21

CE

21

Mansur et al.

2019

3

Prospective

Brazil

19 (19)

NR

51

NR

CE, US, X-ray

22

Pinitkwamdee et al.

2020

1

RCT

Thailand

Group A 16 (22)

Mixed

61.4

7.5

CE,X-ray

      

Group B 15 (16)

Mixed

56.5

12

 

23

Zhang et al.

2020

3

Retrospective

China

Group A 16 (16)

Sports-active

31

≥ 3

CE, US, MRI

      

Group B 17 (17)

Nonsports-active

37

≥ 3

 
  1. Abbreviations: LOE level of evidence, No. number, RCT randomized controlled trial, NR not reported, CE clinical examination, US ultrasound, MRI magnetic resonance imaging