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Table 5 Methylation levels of OPG/RANKL/RANK genes

From: OPG/RANKL/RANK gene methylation among alcohol-induced femoral head necrosis in northern Chinese men

CpG site

Control (N)

Case (N)

Methylation level

p

Control (mean ± SD)

Case (mean ± SD)

OPG5_CpG_11

49

50

0.42 ± 0.18

0.54 ± 0.16

0.001**

RANK2_CpG_20

50

50

0.04 ± 0.03

0.06 ± 0.03

0.032*

RANK3_CpG_5

49

50

0.03 ± 0.01

0.02 ± 0.01

0.010*

RANKL1_CpG_1

49

48

0.64 ± 0.26

0.74 ± 0.19

0.033*

RANKL5_CpG_1

49

50

0.37 ± 0.15

0.79 ± 0.09

0.018*

  1. p value was calculated by the independent samples t test
  2. *p < 0.05
  3. **p < 0.01