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Table 3 Comparison of gene expression patterns of DEGs participated in cartilage growth and regeneration

From: Deer antler extract potentially facilitates xiphoid cartilage growth and regeneration and prevents inflammatory susceptibility by regulating multiple functional genes

Gene name

Expression level (FPKM)

log2 fold change (DAE/blank)

p value

Blank

DAE

Connective tissue growth factor (Ctgf)

1071.72

2155.72

1.01

0

Fibronectin (Fn1)

703.09

1775.29

1.34

0

Aggrecan core protein (Acan)

694.33

1466.54

1.08

0

Lysyl oxidase homolog 4 (Loxl4)

88.25

191.04

1.11

0

Protein CYR61 (Cyr61)

29.43

60.45

1.04

3.52E−44

Sestrin-3 (Sesn3)

16.14

33.95

1.07

2.12E−39

Proteoglycan 4 (Prg4)

15.12

31.45

1.06

1.02E−49

Filamin-B (Flnb)

12.00

30.41

1.34

1.68E−151

Frizzled-7 (Fzd7)

6.71

14.64

1.13

1.47E−18

Bone morphogenetic protein 7 (Bmp7)

4.83

14.31

1.57

1.97E−25

Bone morphogenetic protein 6 (Bmp6)

6.80

13.61

1.00

2.85E−08

Golgin subfamily B member 1 (Golgb1)

4.44

10.82

1.29

4.13E−64

Peptidase inhibitor 15 (Pi15)

3.14

9.50

1.60

4.44E−10

Krueppel-like factor 9 (Klf9)

4.24

9.49

1.16

9.91E−13

Zinc finger protein GLI2 (Gli2)

4.02

8.50

1.08

1.48E−24

Ephrin-A5 (Efna5)

4.05

8.39

1.05

7.06E−11

Zinc finger transcription factor Trps1(Trps1)

1.56

3.72

1.25

1.98E−15