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Fig. 4 | Journal of Orthopaedic Surgery and Research

Fig. 4

From: Silymarin modulates catabolic cytokine expression through Sirt1 and SOX9 in human articular chondrocytes

Fig. 4

Modulation of anabolic and catabolic cytokines by SMN. ELISA assays revealed that treatment with 25 μM SMN reduced the production of catabolic cytokine-stimulated IL-1β, TNF-α, MMP-3 and MMP-9 and increased the production of TIMP-1 in the injured chondrocytes. However, the levels of IL-6, IL-8, IL-10 and TIMP-2 proteins remained unaltered upon SMN addition

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X