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Table 1 The musculoskeletal society 2013 definition of PJI

From: Synovial fluid IL-1β appears useful for the diagnosis of chronic periprosthetic joint infection

MSIS definition of PJIa
1 There is a sinus tract communicating with the prosthesis; or
2 Two positive periprosthetic cultures with phenotypically identical organisms; or
3 When 3 of the following 5 criteria exist:
a. Elevated serum C-reactive protein (CRP) AND erythrocyte sedimentation rate (ESR)
b. Elevated synovial fluid white blood cell (WBC) count OR ++change on leukocyte esterase test strip
c. Elevated synovial fluid polymorphonuclear neutrophil percentage (PMN%)
d. Positive histological analysis of periprosthetic tissue
e. A single positive culture
  1. aOne of the three criteria (1, 2, or 3) must be met for diagnosis of periprosthetic joint infection