Table 3 Comparison of CD-based surgery and other NVG surgery outcomes for pre- and postcollapse-stage ONFH
First author/year | Surgical procedure | Mean age at surgery (years) | Mean follow-up (years) | Number of precollapse ONFH (hips) | Hip survivorship/endpoint | Number of postcollapse ONFH (hips) | Hip survivorship/endpoint |
|---|---|---|---|---|---|---|---|
Seyler [18]/2008 | Light bulb/NVG/rhBMP-7 (3.5 mg) | 35 | 3 | 22 | 81.8% (18/22) Collapse | 17 | 70.5% (12/17) THA |
Wang [19]/2010 | Light bulb/DBM, rhBMP | 32.3 | 2.1 | 67 | 92.5% (62/67) THA | 71 | 88.7% (63/71) THA |
Wang [19]/2010 | CD/BMMNC | 37.5 | 2.3 | 50 | 78% (39/50) Radiological progression | 9 | 66.6% (6/9) Radiological progression |
Zhang [20]/2013 | Light bulb/BG | 31.3 | Minimum 2 | 71 | 85.4% Collapse | 14 | NA |
Lim [21]/2013 | Multiple CD/Stem cell | 36.3 | 5 | 79 | 62.7% (64/102) Surgery or HHS < 75 | 49 | 42.1% (24/57) Surgery or HHS < 75 |
Lim [21]/2013 | Multiple CD | 34.4 | 5 | 23 | 8 | ||
Feng [22]/2019 | CD/iliac BG/VGTF | 33.2 | 9.7 | None | NA | 84 | 92.8% (78/84) THA |
Feng [22]/2019 | CD/iliac BG | 32.8 | 9.8 | None | NA | 51 | 78.4% (40/51) THA |
Tomaru [23]/2019 | CD/BMMNC | 42.2 | 12 | 43 | 51.1% (22/43) Collapse | 37 | 43.2% (16/37) THA |
Liu [24]/2020 | CD/β-TCP | 36 | 5 | 25 | 45.8% (11/24) THA | 22 | 13.0% (3/23) THA |
Present study/2020 | CD/BG/HA, β-TCP | 40.1 | 3 | 1 | 100% (1/1) Collapse | 19 | 63.1% (12/19) THA |