From: The value of the hedgehog signal in osteoblasts in fluoride-induced bone-tissue injury
Groups | The number of cases | The urinary fluoride content(mg/L) | BALP(IU/L) | Ihh | Smo | Gli2 | Runx2 |
---|---|---|---|---|---|---|---|
Control group | 12 | 1.36 ± 0.51 | 27.78 ± 4.09 | 0.73 ± 0.19 | 0.14 ± 0.04 | 0.83 ± 0.19 | 0.37 ± 0.10 |
F group | 12 | 7.60 ± 0.61* | 57.46 ± 3.99* | 1.39 ± 0.36* | 0.40 ± 0.15* | 1.40 ± 0.31* | 0.57 ± 0.19* |
F + Cycl group | 12 | 7.55 ± 0.32* | 53.55 ± 2.22*#& | 0.81 ± 0.28#& | 0.16 ± 0.03#& | 0.75 ± 0.17#& | 0.42 ± 0.09#& |
F + DMSO group | 12 | 7.55 ± 0.19* | 57.56 ± 4.23* | 1.31 ± 0.34* | 0.39 ± 0.10* | 1.26 ± 0.35* | 0.55 ± 0.17* |