Table 3 Gene Ontology analysis of downregulated DEGs-baseline. All enriched terms of the downregulated genes in the peripheral blood of the patients with sciatica at baseline compared with the healthy controls according to the P value. Log10(P) is the log10-based P value.
Category | Term | Description | Log10(P) |
|---|---|---|---|
KEGG pathway | hsa04612 | Antigen processing and presentation | − 4.34 |
GO MF | GO:0030246 | Carbohydrate binding | − 4.07 |
KEGG pathway | hsa04650 | Natural killer cell-mediated cytotoxicity | − 3.63 |
GO BP | GO:0002708 | Positive regulation of lymphocyte-mediated immunity | − 3.92 |
GO BP | GO:0002705 | Positive regulation of leukocyte-mediated immunity | − 3.62 |
GO BP | GO:0002706 | Regulation of lymphocyte-mediated immunity | − 3.46 |
GO BP | GO:0002703 | Regulation of leukocyte-mediated immunity | − 3.08 |
GO BP | GO:0002699 | Positive regulation of immune effector process | − 2.99 |
GO BP | GO:0002449 | Lymphocyte-mediated immunity | − 2.37 |
GO BP | GO:0045089 | Positive regulation of innate immune response | − 2.32 |
GO BP | GO:0045088 | Regulation of innate immune response | − 2.12 |
GO BP | GO:0002697 | Regulation of immune effector process | − 2.08 |
GO BP | GO:0070997 | Neuron death | − 2.40 |