Table 2 Gene Ontology analysis of upregulated DEGs-baseline. The top 15 enriched terms of the upregulated genes in the peripheral blood of the patients with sciatica at baseline compared with the healthy controls according to the P value. Log10(P) is the log10-based P value.
Term | Category | Description | Log10(P) |
|---|---|---|---|
GO:0002274 | GO BP | Myeloid leukocyte activation | − 19.59 |
GO:0002366 | GO BP | Leukocyte activation involved in immune response | − 17.57 |
GO:0002263 | GO BP | Cell activation involved in immune response | − 17.51 |
GO:0043312 | GO BP | Neutrophil degranulation | − 17.42 |
GO:0002283 | GO BP | Neutrophil activation involved in immune response | − 17.35 |
GO:0002275 | GO BP | Myeloid cell activation involved in immune response | − 17.32 |
GO:0042119 | GO BP | Neutrophil activation | − 17.15 |
GO:0002446 | GO BP | Neutrophil-mediated immunity | − 17.12 |
GO:0036230 | GO BP | Granulocyte activation | − 17.02 |
GO:0043299 | GO BP | Leukocyte degranulation | − 16.44 |
GO:0002444 | GO BP | Myeloid leukocyte-mediated immunity | − 16.10 |
GO:0045055 | GO BP | Regulated exocytosis | − 14.36 |
GO:0042581 | GO CC | Specific granule | − 14.34 |
GO:0070820 | GO CC | Tertiary granule | − 12.84 |
GO:0035580 | GO CC | Specific granule lumen | − 8.99 |