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Table 1 Characteristics of studies included in the meta-analysis. FTS fast track surgery, NA not applicable

From: The efficacy and safety of fast track surgery (FTS) in patients after hip fracture surgery: a meta-analysis

Author Publication year Characteristics of study population Hip fracture surgery FTS measures Follow-up Endpoints
Sample size (n) Age (years) Women, No. (%)
E C E C E C E C
Li [21] 2016 60 60 72.05±6.37 70.43±5.83 21 (35.00) 24 (40.00) Total hip arthroplasty; hemiarthroplasty Total hip arthroplasty; hemiarthroplasty 1, 2, 3, 4, 5, 7, 8 8 weeks LOS, Harris hip joint function score, satisfaction, VTE, dislocation of prosthesis
Tian [22] 2016 40 40 NA NA NA NA Total hip arthroplasty Total hip arthroplasty 1, 2, 8 6 months LOS, respiratory, incision infection
Xu [23] 2016 55 55 73.58±5.27 73.45±5.46 32 (58.18) 34 (61.82) Hip arthroplasty; internal fixation Hip arthroplasty; internal fixation 1, 2, 3, 4, 5, 6, 7, 8 6 months LOS, Harris hip joint function score, respiratory, urinary tract infection, VTE, pressure sores, dislocation of prosthesis
Yang [24] 2016 126 132 64.2±9.4 66.3±8.6 70 (27.1) 67 (26.0) Unilateral hip arthroplasty Unilateral hip arthroplasty 1, 2, 6, 7, 8 3 months LOS, VTE, dislocation of prosthesis
Zhang [25] 2016 56 52 73.91±7.18 74.28±6.85 38 (67.86) 37 (71.15) Hip arthroplasty; internal fixation Hip arthroplasty; internal fixation 1, 4, 6, 7, 8 NA LOS, Harris hip joint function score, VAS, respiratory, urinary tract infection, VTE, pressure sores
Chen 1 [26] 2017 106 92 68.5±4.1 67.7±4.3 61 (57.55) 50 (54.35) NA NA 1, 2, 4, 5, 6, 7, 8 NA LOS, satisfaction, cost, VTE, pressure sores, constipation
Chen 2 [27] 2017 40 40 NA NA NA NA Unilateral hip arthroplasty Unilateral hip arthroplasty 1, 7, 8 3d, 7d, 1 month, 3 months Harris hip joint function score, VAS, respiratory, VTE, dislocation of prosthesis
Fu [28] 2017 40 40 NA NA NA NA NA NA 1, 2, 4, 6, 7, 8 2 weeks, 1 month, 3 months, 6 months Harris hip joint function score, VAS, respiratory, urinary tract infection, VTE, pressure sores
Li [29] 2017 45 45 NA NA NA NA Hip arthroplasty Hip arthroplasty 2, 4, 8 8 weeks Harris hip joint function score
Liu [30] 2017 41 41 53.08±2.07 56.02±1.85 12(29.27) 14(34.15) Hip arthroplasty Hip arthroplasty 3, 4, 6, 8 6 months LOS, respiratory, urinary tract infection, VTE, incision infection
Wan [31] 2017 43 43 NA NA NA NA Hip arthroplasty Hip arthroplasty 1, 4, 7, 8 NA LOS
Wei [32] 2017 50 50 74.1±6.3 73.2±5.2 NA NA NA NA 1, 2, 3, 4, 5, 6, 7, 8 NA LOS, satisfaction, VTE
Yu [33] 2017 40 40 NA NA NA NA Hip arthroplasty Hip arthroplasty 3, 4, 5, 6, 7, 8 6 months LOS, Harris hip joint function score, cost, respiratory, urinary tract infection, VTE, incision infection
Zhang [34] 2017 43 43 70.13±3.75 69.38±3.46 18 (41.86) 17 (39.53) Hip arthroplasty Hip arthroplasty 1, 3, 4, 7, 8 NA LOS, Harris hip joint function score, VTE, pressure sores
Zou [35] 2017 40 40 NA NA NA NA NA NA 8 NA LOS, Harris hip joint function score, respiratory, urinary tract infection, VTE
Ding [36] 2018 45 45 66.2±3.5 65.8±3.4 20 (44.44) 19 (42.22) Total hip arthroplasty, unilateral hip arthroplasty Total hip arthroplasty, unilateral hip arthroplasty 1, 2, 4, 5, 7, 8 NA LOS, cost, respiratory, urinary tract infection, VTE, constipation
Jin [37] 2018 40 40 70.3±4.5 69.3±4.2 17 (42.50) 18 (45.00) Hip arthroplasty, reduction of hip fracture Hip arthroplasty, reduction of hip fracture 4, 7, 8 NA LOS, VAS
Li 1 [38] 2018 41 41 63.5±3.5 64.5±4.5 18 (43.90) 19 (46.34) Hip arthroplasty Hip arthroplasty 1, 4, 6, 7, 8 NA Harris hip joint function score, VTE
Li 2 [39] 2018 60 60 78.77±7.62 76.33±8.75 32 (53.33) 29 (48.33) NA NA 3, 4, 6, 8 NA LOS, respiratory, urinary tract infection, VTE, pressure sores
Liu [40] 2018 53 53 72.42±2.29 72.39±2.25 17 (32.08) 20 (37.74) NA NA 1, 4, 7, 8 NA VAS
Qian [41] 2018 41 41 81.35±4.77 81.21±4.46 17 (41.46) 18 (43.90) Reduction of hip fracture, hip arthroplasty Reduction of hip fracture, hip arthroplasty 1, 4, 7, 8 5 months Harris hip joint function score, VAS
Wang [42] 2018 47 46 79.47±8.36 79.58±8.42 22 (46.81) 21 (45.65) Hip arthroplasty Hip arthroplasty 1, 4, 5, 7, 8 NA LOS, satisfaction, the leaving bed time, urinary tract infection, VTE, incision infection
Yang 1 [43] 2018 50 50 58.52±8.53 57.96±8.41 25 (50.00) 24 (48.00) Hip arthroplasty Hip arthroplasty 1, 2, 3, 5, 7, 8 NA LOS, Harris hip joint function score, VTE, pressure sores
Yang [44] 2018 40 40 57.4 ±11.3 58.3 ±12.9 22 (55.00) 19 (47.50) Hip arthroplasty Hip arthroplasty 1, 2, 4, 7, 8 1d, 3d, 7d VAS, the leaving bed time, VTE, incision infection
You [45] 2018 100 100 86±5.1 82±5.3 40 (40.00) 42 (42.00) PFNA internal fixation PFNA internal fixation 1, 2, 3, 4, 5, 6, 7, 8 NA LOS, satisfaction, cost
Zang [46] 2018 40 40 71.5±1.5 70.5±3.0 19 (47.50) 20 (50.00) Femoral head replacement Femoral head replacement 1, 2, 4, 7, 8 18 months Satisfaction
Zhai [47] 2018 40 40 73.45±2.54 72.99±3.14 19 (47.50) 22 (55.00) NA NA 1, 5, 7, 8 NA Satisfaction, VTE, pressure sores
Zheng [48] 2018 45 45 71.16±5.05 71.08±5.07 19 (42.22) 20 (44.44) Hip arthroplasty Hip arthroplasty 4, 6, 7, 8 6 months LOS, Harris hip joint function score, cost, VTE
Zuo [49] 2018 40 41 72.36±10.48 71.72±10.2 4 19 (47.50) 18 (43.90) Hip arthroplasty Hip arthroplasty 1, 4, 5, 6, 8 3 months Harris hip joint function score, respiratory, VTE
Bai [50] 2019 64 64 NA NA NA NA Total hip arthroplasty, unilateral hip arthroplasty Total hip arthroplasty, unilateral hip arthroplasty 1, 2, 4, 5, 7, 8 3 months Harris hip joint function score, VTE, pressure sores, dislocation of prosthesis
Bao [51] 2019 49 48 NA NA NA NA NA NA 2, 4, 5, 6, 7, 8 6 months Harris hip joint function score, VAS, respiratory, urinary tract infection, VTE, pressure sores
Chen [52] 2019 44 43 68.21±6.44 65.58±6.34 29 (65.91) 28 (65.12) Hip arthroplasty Hip arthroplasty 1, 3, 4, 7, 8 NA LOS, satisfaction, the leaving bed time, cost
Fusco [53] 2019 40 40 NA NA 0 0 Hip arthroplasty Hip arthroplasty 8 12 months Cost
Guo 1 [54] 2019 51 51 72.6±3.5 72.3±3.4 18 (35.29) 21 (41.18) Hip arthroplasty Hip arthroplasty 1, 2, 3, 4, 5, 7, 8 7d LOS, respiratory, VTE, incision infection
Guo 2 [55] 2019 42 42 82.24±4.58 82.29±4.73 17 (40.48) 18 (42.86) NA NA 1, 4, 7, 8 5 months Harris hip joint function score
He [56] 2019 43 43 83.85±3.79 82.47±3.18 19 (44.19) 21 (48.84) Reduction of hip fracture, hip arthroplasty Reduction of hip fracture, hip arthroplasty 1, 4, 8 NA LOS, Harris hip joint function score, VAS, cost, urinary tract infection, VTE, pressure sores
Huang [57] 2019 40 40 NA NA NA NA Hip arthroplasty Hip arthroplasty 1, 8 NA LOS
Jia [58] 2019 60 60 NA NA NA NA Hip arthroplasty Hip arthroplasty 1, 2, 4, 5, 6, 8 NA LOS, VAS, satisfaction, the leaving bed time, VTE, pressure sores
Jiang [59] 2019 43 43 46.5±2.4 41.5±5.7 20 (46.51) 24 (55.81) NA NA 1, 4, 7, 8 5 months Satisfaction
Jin 1 [60] 2019 43 43 68.5±5.6 66.4±5.6 23 (53.49) 21 (48.84) NA NA 1, 4, 5, 8 NA LOS, satisfaction, cost
Jin 2 [61] 2019 132 146 73.5±7.6 71.7±5.2 103 (78.03) 101 (69.18) Hip arthroplasty Hip arthroplasty 4, 5, 6, 7, 8 1d, 2d, 1 week The leaving bed time, respiratory, urinary tract infection, VTE, incision infection
Li [62] 2019 40 40 62.30±10.40 62.25±10.34 18 (45.00) 17 (42.50) Hip arthroplasty Hip arthroplasty 1, 2, 3, 4, 6, 7, 8 1 month, 3 months LOS, cost
Liang [63] 2019 53 53 76.7±2.4 77.9±2.7 24 (45.28) 21 (39.63) NA NA 1, 4, 5, 6, 7, 8 3 months Harris hip joint function score, respiratory, urinary tract infection, VTE, pressure sores
Liu [64] 2019 60 60 81.9±4.9 81.6±5.2 17 (28.33) 13 (21.67) NA NA 3, 5, 6, 8 NA LOS
Sun [65] 2019 45 45 69.24±2.89 69.78±2.82 13 (28.89) 14 (31.11) NA NA 1, 3, 4, 5, 6, 7, 8 NA Harris hip joint function score, satisfaction, respiratory, urinary tract infection, VTE, pressure sores
Xiao [66] 2019 40 40 72.11±4.35 71.39±4.15 17 (42.50) 19 (47.50) Unilateral hip arthroplasty Unilateral hip arthroplasty 1, 4, 8 NA VTE, constipation
Yang [67] 2019 56 56 70.24±17.76 71.57±17.43 33 (58.93) 32 (57.14) Hip arthroplasty; Internal fixation Hip arthroplasty; Internal fixation 1, 7, 8 NA LOS
Yu [68] 2019 66 60 73.94±3.87 73.77±4.25 40 (60.60) 37 (61.67) Hip arthroplasty; Internal fixation Hip arthroplasty; Internal fixation 1, 2, 4, 5, 7, 8 3 months LOS, satisfaction, respiratory, urinary tract infection, VTE, dislocation of prosthesis
Zhang [69] 2019 49 49 73.14±2.28 73.75±2.54 20 (40.82) 22 (44.90) Hip arthroplasty Hip arthroplasty 4, 6, 8 NA LOS, satisfaction
Zhu [70] 2019 90 90 72.1±8.3 72.4±8.6 52 (57.78) 50 (55.56) NA NA 1, 4, 6, 7, 8 6 months Harris hip joint function score, VAS, respiratory, urinary tract infection, VTE, pressure sores, incision infection
Borges [71] 2020 1487 1483 NA NA 1031 (69.33) 1022 (68.91) Open reduction and internal fixation, hip arthroplasty Open reduction and internal fixation, hip arthroplasty NA NA Respiratory, VTE, pressure sores
Du [72] 2020 50 50 83.1±2.4 84.6±2.8 38 (76.00) 34 (68.00) Total hip arthroplasty Total hip arthroplasty 1, 4, 5, 6, 7, 8 6 months Harris hip joint function score, VAS, the leaving bed time, urinary tract infection, VTE, pressure sores, dislocation of prosthesis
Ge [73] 2020 40 40 NA NA 27 (67.50) 28 (70.00) Hip arthroplasty Hip arthroplasty 1, 3, 4, 5, 6, 7, 8 3 months LOS, Harris hip joint function score, VTE, constipation
Jiang [74] 2020 40 40 NA NA NA NA Internal fixation Internal fixation 8 2 weeks, 1 month, 3 months Harris hip joint function score, respiratory, urinary tract infection, VTE, constipation
Liang [75] 2020 47 47 46.58±5.97 47.83±5.52 20 (42.55) 21 (44.68) Hip arthroplasty Hip arthroplasty 1, 3, 4, 7, 8 NA LOS, satisfaction, the leaving bed time, cost
Yu [76] 2020 47 47 76.5±3.2 75.9±3.8 19 (40.43) 20 (42.55) NA NA 1, 3, 4, 6, 7 NA LOS, VAS, satisfaction, the leaving bed time, respiratory, urinary tract infection, VTE, pressure sores
Zheng [77] 2020 80 80 59.66±5.26 59.63±5.14 33 (41.25) 35 (43.75) Hip arthroplasty Hip arthroplasty 1, 7, 8 1 month, 6 months Harris hip joint function score
  1. FTS fast track surgery, NA not applicable. FTS measures: (1) preoperative propaganda and education/psychological counseling, (2) the method of optimizing anesthesia, (3) simplification of routine intestinal preparation before operation, (4) perioperative nutrition management, (5) perioperative heat preservation, (6) rational use of drainage tube and catheter, (7) postoperative analgesia, and (8) early postoperative normative functional exercise