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Table 1 Main characteristics of the 11 included studies

From: Intra-articular magnesium to alleviate postoperative pain after arthroscopic knee surgery: a meta-analysis of randomized controlled trials

Author, year Country Groups (n) Interventions Age (y), %Males Type of arthroscopy Anesthesia Main outcomes
Sadoni, 2017 [28] Iran Mg: 51 Mg 1 g + saline to 20 ml 30.6 ± 7.6, 82.3% Meniscectomy General VAS, AC, AD
P: 43 Saline 20 ml 29.9 ± 9.5, 79.0%
Devi, 2018 [29] India Mg + B: 18 Mg 10 mg/kg + 0.25% B to 20 ml 33.44 ± 10.87, 72.2% Arthroscopy Spinal VAS, AC
B: 18 0.25% B 20 ml 37.22 ± 13.36, 55.5%
Abdulatif, 2015 [30] Egypt Mg: 28 Mg 1 g + saline to 20 ml 34.6 ± 9.3, 60.7% ACL reconstruction FNB + General VAS, AC, AD, SE
P: 27 Saline 20 ml 35.0 ± 10.4, 74.0%
FAROUK, 2009 [31] Egypt Mg + B: 20 Mg 0.15 g + 0.25% B to 20 ml 36 ± 6, 90% Meniscectomy General VAS, AC, AD
B: 20 0.25% B 20 ml 35 ± 7, 80%
Radwan, 2012 [32] Egypt Mg: 20 Mg 0.8 g + saline to 20 ml 31.10 ± 7.90, 85% Meniscectomy General VAS, AC, AD, SE
B: 20 0.5% B 20 ml 32.20 ± 9.62, 90%
Koltka, 2011 [33] Turkey Mg: 30 Mg 0.5 g + saline to 20 ml 48.4 ± 11, 30% Meniscectomy General NRS, AC, AD
P: 30 Saline 20 ml 46.0 ± 15.6, 36.6%
Suhrita, 2009 [34] Kolkata Mg + B: 30 Mg 0.5 g+ 0.25% B to 20 ml 37.9 ± 11.8, 36.6% Meniscectomy, Ligament repair General VAS, AC, AD, SE
B: 30 0.25% B + saline to 20 ml 36.8 ± 10.6, 70%
Kizilcik, 2017 [35] Turkey Mg + LB: 32 Mg 1.5 g + LB 50 mg to 15 ml 43.06 ± 13.19, 68.7% Meniscectomy General VAS, AC, SE
LB: 32 LB 100 mg 10 ml 40.06 ± 9.24, 75%
Bondok, 2006 [36] Egypt Mg: 30 Mg 0.5 g + saline to 10 ml 27 ± 4, 100% Meniscectomy General VAS, AC, AD
P: 30 Saline 10 ml 25 ± 4, 100%
Elsharnouby, 2008 [37] Egypt Mg: 27
P: 27
Mg 1 g + saline to 20 ml
Saline 20 ml
39 ± 12, 11.1%
41 ± 13, 14.8%
Meniscectomy General VAS, AC, AD
Mg + B: 27
B: 27
Mg 1 g + 0.25% B to 20 ml
0.25% B 20 ml
40 ± 11, 3.7%
45 ± 9, 7.4%
Venkateshamurthy, 2018 [38] India Mg + B: 30 Mg 1 g + 0.25% B to 30 ml Un Arthroscopy General VAS, AC, AD
B: 30 0.5% B + saline to 30 ml
  1. Mg magnesium sulfate, B bupivacaine, P placebo, LB levobupivacaine, ACL anterior cruciate ligament, Un unknown, FNB femoral nerve block, VAS visual analog scale score, NRS numeric rating scale, AC analgesic consumption, AD analgesic consumption duration, SE side effects