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Fig. 6 | Journal of Orthopaedic Surgery and Research

Fig. 6

From: Secreted frizzled-related protein 5 (SFRP5) protects ATDC5 cells against LPS-induced inflammation and apoptosis via inhibiting Wnt5a/JNK pathway

Fig. 6

Overexpression of Wnt5a blunts the inhibitory effect of SFRP5 elevation on LPS-induced apoptosis in ATDC5 cells. a Representative images for TUNEL staining, apoptotic cells were stained with dark brown (× 200). b Representative blots and quantitative analysis for Bcl-2, Bax, and cleaved caspase 3. c The representative blots and quantitative analysis for Wnt5a, JNK, and phosphorylated JNK. **P < 0.01, ***P < 0.001. Ov, overexpression; NC, negative control; ns, no significance

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X