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Fig. 5 | Journal of Orthopaedic Surgery and Research

Fig. 5

From: Secreted frizzled-related protein 5 (SFRP5) protects ATDC5 cells against LPS-induced inflammation and apoptosis via inhibiting Wnt5a/JNK pathway

Fig. 5

Overexpression of Wnt5a blunts the inhibitory effect of SFRP5 elevation on LPS-induced inflammation in ATDC5 cells. a The protein expression of Wnt5a in ATDC5 cells or cells that transfected with NC or ov-Wnt5a vectors. b The concentration of inflammatory cytokines including TNF-α, IL-1β, and IL-6 in the culture supernatants of ATDC5 cells. c The level of ROS relative to control group in ATDC5 cells. **P < 0.01, ***P < 0.001. Ov, overexpression; NC, negative control; ns, no significance

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