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Fig. 2 | Journal of Orthopaedic Surgery and Research

Fig. 2

From: Secreted frizzled-related protein 5 (SFRP5) protects ATDC5 cells against LPS-induced inflammation and apoptosis via inhibiting Wnt5a/JNK pathway

Fig. 2

Overexpression of SFRP5 inhibits LPS-triggered inflammation in ATDC5 cells. a The cell viability of ATDC5 cells that exposed to different concentrations of LPS. b, c The protein (b) and mRNA (c) level of SFRP5 in ATDC5 cells before and after SFRP5 overexpression in the presence of 5 μg/ml LPS treatment. d The concentration of inflammatory cytokines including TNF-α, IL-1β, and IL-6 in the culture supernatants of ATDC5 cells. e The level of ROS relative to control group in ATDC5 cells. *P < 0.05, ***P < 0.001. Ov, overexpression; NC, negative control; ns, no significance

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X