Skip to main content
Fig. 6 | Journal of Orthopaedic Surgery and Research

Fig. 6

From: Mesenchymal stem cell-originated exosomal lncRNA HAND2-AS1 impairs rheumatoid arthritis fibroblast-like synoviocyte activation through miR-143-3p/TNFAIP3/NF-κB pathway

Fig. 6

HAND2-AS1 is highly enriched in exosomes derived from HAND2-AS1-transfected hMSCs. a Representative TEM images of exosomes from hMSCs. b Exosomes isolated from hMSCs underwent a NTA to determine exosomal size distribution. c Western blot analysis of CD63, CD81, TSG101, and GRP94 expression in isolated exosomes and the lysate of hMSCs. d qRT-PCR analysis of HAND2-AS1 level in hMSCs transfected with vector or HAND2-AS1. e qRT-PCR analysis of HAND2-AS1expresison in exosomes derived from transfected hMSCs. f qRT-PCR analysis of HAND2-AS1expresison in MH7A cells co-cultured with HAND2-AS1-Exos or vector-Exos. ***P < 0.0001

Back to article page

Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X