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Fig. 5 | Journal of Orthopaedic Surgery and Research

Fig. 5

From: MiR-140-3p inhibits the cell viability and promotes apoptosis of synovial fibroblasts in rheumatoid arthritis through targeting sirtuin 3

Fig. 5

SIRT3 overexpression reversed the effect of miR-140-3p mimic on SRIT3 expression, cell viability, and cell apoptosis. a The expression of SIRT3 in MH7A cells was detected by RT-qPCR; GAPDH was used as an internal control. b The cell viability of MH7A cells was detected by CCK-8 assays. c, d The cell apoptosis of MH7A cells was detected by flow cytometry. All experiments were conducted three times. (*P < 0.05, **P < 0.01,***P < 0.001, vs. mimic control; ##P < 0.01,###P < 0.001, vs. mimic; ^^P < 0. 01,^^^P < 0.001, vs. mimic control +SRIT3). (SIRT3, sirtuin 3)

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