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Fig. 3 | Journal of Orthopaedic Surgery and Research

Fig. 3

From: MiR-140-3p inhibits the cell viability and promotes apoptosis of synovial fibroblasts in rheumatoid arthritis through targeting sirtuin 3

Fig. 3

MiR-140-3p regulated the SIRT3 expression, cell viability, and cell apoptosis in MH7A cells. a The expression of miR-140-3p in MH7A cells was detected by RT-qPCR; U6 was used as an internal control. b The expression of SIRT3 in MH7A cells was detected by RT-qPCR; GAPDH was used as an internal control. c, d The expression of SIRT3 in MH7A cells was detected by western blot. e The cell viability of MH7A cells was detected by CCK-8 assays. f, g The cell apoptosis of MH7A cells was detected by flow cytometry. All experiments were conducted three times. (*P < 0.05, ***P < 0.001, vs. mimic control; ^^P < 0.01, ^^^P < 0.001, vs. inhibitor control) (SIRT3, sirtuin 3)

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X