Table 3 Trend of drug resistance rate of E. coli in orthopedics from 2012 to 2017

Amikacin

16.7 (4/24)

8.8 (3/34)

3.0 (1/33)

10.5 (4/38)

10.7 (3/28)

0.0 (0/22)

5.651

0.311

Ceftazidime

28.6 (8/28)

51.5 (17/33)

58.1 (18/31)

45.9 (17/37)

42.9 (12/28)

45.5 (10/22)

5.760

0.330

Cefepime

26.7 (8/30)

33.3 (11/33)

48.5 (16/33)

48.6 (18/37)

42.9 (9/21)

…

5.033

0.284

Cefoxitin

…

…

25.0 (4/16)

12.5 (3/24)

24.0 (6/25)

10.0 (2/20)

2.205

0.488

Levofloxacin

53.3 (16/30)

51.5 (17/33)

51.5 (17/33)

36.8 (14/38)

60.7 (17/28)

63.6 (14/22)

5.558

0.352

Tobramycin

27.3 (6/22)

23.5 (8/34)

25.0 (6/24)

28.6 (10/35)

28.6 (8/28)

36.4 (8/22)

1.226

0.942

Cefperazone-sulbactam

7.1 (2/28)

3.0 (1/33)

8.3 (2/24)

0.0 (0/17)

10.5 (2/19)

10.0 (2/20)

3.139

0.709

Ciprofloxacin

53.3 (16/30)

51.5 (17/33)

57.6 (19/33)

39.5 (15/38)

42.1 (16/28)

45.5 (10/22)

3.337

0.648

Gentamicin

60.0 (18/30)

54.5 (18/33)

51.5 (17/33)

34.2 (13/38)

46.4 (13/28)

45.5 (10/22)

5.427

0.366

Cotrimoxazole

47.1 (16/34)

67.6 (23/34)

75.8 (25/33)

57.1 (20/35)

57.1 (16/28)

36.4 (8/22)

11.493

0.042

Meropenem

0.0 (0/28)

3.3 (1/30)

6.1 (2/33)

8.3 (2/24)

19.2 (5/26)

10.0 (2/20)

7.476

0.124

Imipenem

6.7 (2/30)

2.9 (1/34)

3.0 (1/33)

0.0 (0/38)

17.9 (5/28)

9.1 (2/22)

9.130

0.043

Ampicillin

93.3 (28/30)

97.0 (33/34)

93.8 (30/32)

91.9 (34/37)

92.9 (26/28)

81.8 (18/22)

4.108

0.530

Piperacillin-tazobactam

0.0 (0/30)

2.9 (1/34)

3.0 (1/33)

0.0 (0/38)

17.9 (5/28)

18.2 (4/22)

14.370

0.010