Fig. 2

Many key genes and pathways are involved in the variant pathogenesis of OA between Tibetans and Chinese Han. a, b The Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis were performed by using the data of differently expressed mRNA in the cartilage tissues of Tibetans (n = 5) comparing with those of Chinese Han (n = 3) based on the DAVID database (https://david.ncifcrf.gov). The top 30 significant cellular processes and signaling pathways were demonstrated by GO a and KEGG b enrichment scatter plot. The y-axis was the name of cellular processes or signaling pathways, and the x-axis was the gene ratio. The size of the dot revealed the number mRNAs