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Table 2 Risk of bias of included randomized and non-randomized controlled trials

From: Cannabinoids and orthopedic surgery: a systematic review of therapeutic studies

Randomized controlled trials

Study

Randomization

Deviation from intended effects

Missing outcome data

Measurement of outcome

Selection of the reported result

Overall

Beaulieu et al. [17]

High

SC

Low

Low

SC

High

Hunter et al.a [18]

SC

SC

SC

Low

SC

SC

Jain et al. [19]

Low

Low

Low

Low

SC

SC

Levin et al. [20]

Low

Low

Low

Low

Low

Low

Crossover trials

Study

Randomization

Carry-over

Deviation from intended intervention

Missing outcome data

Measurement of outcome

Selection of reported results

Overall

Notcutt et al. [22]

Low

SC

Low

Low

Low

Low

SC

Yassin et al. [23]

High

SC

SC

Low

SC

Low

High

Yassin et al. [24]

High

SC

SC

Low

SC

Low

High

Comparative parallel non-randomized trials

Study

Confounding

Selection

Classification

Deviation from intended intervention

Missing Data

Measurement of outcomes

Selection of reported results

Overall

Hickernell et al. [9]

Moderate

Low

Low

Moderate

Low

Moderate

Low

Moderate

Holdcroft et al. [25]

Moderate

Low

Low

Low

Low

Moderate

Low

Moderate

Ware et al. [21]

Moderate

Moderate

Low

Low

Low

Low

Low

Moderate

  1. This table contains the bias assessment of included randomized controlled trials and comparative non-randomized studies. The headings are individual domains outlined in the RoB 2 and ROBINS-I tools
  2. aAbstract only