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Fig. 4 | Journal of Orthopaedic Surgery and Research

Fig. 4

From: Bioinformatics analysis of miRNA and mRNA expression profiles to reveal the key miRNAs and genes in osteoarthritis

Fig. 4

Regulatory networks. a The miRNA-gene network. b The miRNA-transcription factor (TF)-gene regulatory network. Circles, inverted triangles, and diamonds represent genes, miRNAs, and TFs, respectively. Red and blue represent upregulated and downregulated genes, respectively. T shapes, lines, and arrows represent miRNA-gene regulatory relationships, protein-protein interactions, and TF-gene regulatory relationships, respectively

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